As an excellent model organism, despite the many experimental advantages of C. elegans, the tough cuticle surrounding the animal and the small size of most somatic cells limit the study of cell-specific gene expression and function at the molecular level. Therefore, large-scale isolation and culture of primary worm cells are required. Isolated C. elegans cells are also an important model system and can be used to study electrophysiology, cell autonomous development/behavior, and analysis of single-cell profiling. CD BioSciences has developed an efficient and technically simple platform for large-scale isolation and primary culture C. elegans cells from both embryos and all four larval stages, hoping to meet the specific needs of clients' research.
Cell isolation and culture are essential tools for the study of cell function. Isolated cells have several advantages that can't be replaced with whole animals or even tissue explants, such as growth under controlled conditions, being manipulated and imaged at a level of resolution. With the development of science and technology, large-scale isolation and culture methods have been widely exploited for the study of C. elegans, involving primary C. elegans cells from embryos and to all larval stages.
As experts in C. elegans research, CD BioSciences utilizes expertise and extensive experience to provide C. elegans cell isolation and culture services to clients worldwide, providing a new foundation for a wide range of experimental opportunities. Our services include, but are not limited to:
Eggs are isolated from gravid adults and hatched overnight.
L1-L4 worms are isolated separately.
C. elegans are treated with SDS-DTT.
Cells are isolated on ice and cultured in culture medium.
As a leading global provider of customized services, CD BioSciences is committed to providing you with high-quality services and innovative products on C. elegans to meet the unused needs of our clients. From project consultation to delivery of results, our experienced scientists are involved throughout the entire process to break through difficulties and advance research progress. If you are interested in our services or have any other questions, please feel free to contact us.