WMICROTRACKER ONE

Product Brochure

WMicrotracker ONE is optimized for measurements of animals cultured in a liquid medium by using a 96- or 384-well plate format. Compatible with most small animal species [from 100 um to 3 mm size]. Useful for Drug screening, Mutant/RNAi screening, Oxidative Stress, Neurodegeneration, Developmental toxicology, Ecotoxicity experiments and more.

HOW IT WORKS

Based on an innovative system of 384 IR microbeams, the system detects the small interferences generated by the organisms present in the sample. In this way, a pattern of activity is recorded and processed using software specifically designed for real-time data acquisition. The digital analysis of signal changes (proportional to light intensity) allows us to detect the movement of the organism as it passes through the beam of light. An algorithmic software calculates the number of activity events per unit time.

With WMicrotracker-ONE, You Can Obtain Fast And Accurate Measurements Of The Movement Of C. elegans On Multi-well Plates.

Obtaining results is very straightforward. The data is robust, reproducible, and free from user bias. A long kinetic recording can be performed entirely automatically.

1. FOR WHAT?
Experiments based on measurements of behavior and viability. Mainly designed for liquid culture medium and multi-well plates of 96 and 384 wells. Flexible animal models: 0.1-10 mm. which have swimming movements.

2. FOR WHOM?
For any early stage or experienced laboratory. With affordable price for small laboratories. Focused on a varied field of experimentation. Intended for the academic and research sector, university teaching and for companies.

3. HOW DOES IT WORK?
The system detects the movement of organisms through the interference caused by them in an array of micro beams of infrared light. (Patented Technology # US12515723, EP208640881).

FEATURES

Reliable Screening of Dye Phototoxicity by Using a Caenorhabditis elegans Fast Bioassay.
Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.
Bioactivity Of Nano-silver In Caenorhabditis Elegans: Effects Of Size, Coat, And Shape.
An automated tracking system for Caenorhabditis elegans locomotor behavior and circadian studies application.

TECHNICAL SPECIFICATIONS

WMicrotracker^® Technical Specification Comparison

FEATURES	TECHNICAL E-SPECIFICATION
FEATURES	ONE	ARENA
Technology	Scattering of infrared light microbeams detected by phototransistor receptors. Non-invasive technology: very low power infrared radiation.	Temporary interferometry of light microbeams detected by cameras. Non-invasive technology: very low power infrared radiation.
Patent	Argentinian National Research Council CONICET (P20060105084AR, PCT/IB2007/054628, EPO & US patent granted).	Argentinian National Research Council CONICET (P20060105084AR, PCT/IB2007/054628, P20190100121AR, PCT/ES2020/070029, EPO & US patent granted).
Sensing channels per well	2 microbeams in 96 wells (flat) format. 1 microbeam in 96 well (U) format. 1 microbeam in 384 well format.	Array of thousands of microbeams.
Organism	Detection of good swimmer small animals (At least 500 µm in size). Examples: C. elegans L1-Adult.	Detection of good movement small animals (At least 1000 µm in size). Examples: C. elegans L4-Adult.
Data processing	Fast data processing: lt calculates the movement in real time, with 2 minutes time block resolution.	Fast data processing: lt calculates the movement in real time, with 5 minutes time block resolution.
Time in the market (Until Dic 2020)	10 years in the market 100 laboratories and academic publications	2 years in the market 15 laboratories 2 academic publications
Temperature control	Monitoring without control.	Monitoring and Programmable temperature control 20-37 °C.

	TECH	Label free measures	Species flexibility	Liquid medium	Agar medium	Parallel throughput	iRNA
WMICROTRACKER^® ONE	IR microbeam/ Phototransistor receptors	✓	✓	✓	x	384	✓
WMICROTRACKER^® ARENA	IR microbeam/ camera receptors	✓	✓	✓	✓	24	✓
Bug/Worms trackers	Video recognition	✓	✓	x	✓	1	r
Worm-scan	Photo flatbed Scanner	✓	✓	x	✓	12	✓
Lifespan Machine	Scanner monitor	✓	x	x	✓	16	✓
Flow cytometer	Fluorescence detection	x	x	✓	x	96 (1/time)	✓
Microfluidic chips	Immobilization and microscopy	✓	x	✓	x	48	x

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