Extrachromosomal arrays are formed by injecting linear or supercoiled DNA into the germline syncytium resulting in large hereditary DNA structures that contain many copies of the injected DNA propagated as one or more ring chromosomes. Precise genetic manipulation using extrachromosomal arrays allows for the introduction of target genes into C. elegans. Over the years, CD BioSciences has focused on C. elegans research, and the customized services we provide help industry leaders generate high-quality, reproducible data to answer their questions in the corresponding research fields.
As self-replicating genetic elements that exist outside of an organism's chromosomes, extrachromosomal arrays can be stably maintained across generations, allowing for controlled and targeted genetic modifications within an organism. Arrays have the advantage that they are easy to generate and can drive high transgene expression in somatic cells. Integration of extrachromosomal arrays, which are generally composed of multiple copies of the transgenes, allows for the overexpression of the respective transgenes. Arrays and integration provide a flexible and efficient method for gene editing in C. elegans, facilitating studies of gene function and regulation.
Using our proven and advanced technology platform, you can choose to express a variety of configurations of transgenes, such as but not limited to:
As an expert in C. elegans research, CD BioSciences provides C. elegans array and integration service to passionate researchers around the world utilizing advanced and proven technology platforms and expertise to accelerate research progress.
CD BioSciences has the advanced equipment, expertise, and innovative technology platform in C. elegans gene editing to provide solutions tailored to your project and specific needs. If you are interested in our services or have any additional questions, please feel free to contact us.