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| Host Species | Rat |
| Species Reactivity | C. elegans, Human, Mouse, Cattle, Dog, Fruit fly, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Rat, Yeast, S. cerevisiae |
| Conjugate | Conjugated available |
| Clone Number | NW0145 |
| Specificity | Detects ~60 kDa. Also detects ~92 kDa. Cross reactivity with human HSP60 has been observed with this antibody in immunoblot analysis. Reacts weakly with Saccharomyces cerevisiae, consistent with the ep. |
| Immunogen | Recombinant mouse TCP1α protein fragment (carboxy terminal region). |
| Format | Liquid or Lyophilized |
| Cellular Localization | Cytoplasm |
| Purification | Protein G purified |
| Product Overview | Rat Anti-Yeast TCP1-alpha (clone NW0145) Antibody is a Rat antibody against the epitope of the TCP1-alpha. It can be used for TCP1-alpha detection in Western Blot, Immunofluorescence, Immunoprecipitation, Flow Cytometry. |
| Availability | Made-to-order |
| Target Name | TCP1-alpha |
| Gene ID | 21454 |
| UniProt ID | P11983 |
| Introduction | T-complex polypeptide-1 (TCP1) is a ~60 kDa protein that is constitutively expressed in almost all eukaryotic cells and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of hetero-oligomeric chaperone proteins, and it is known to be involved in the folding of actin and tubulin. The protein family called chaperones plays a role in identifying and stabilizing peptide intermediates during folding, assembly and disassembly, and has many characteristics with heat shock protein 70 (HSP 70), including high abundance, environmental stress induction and ATPase activity. The chaperone protein family includes mitochondrial HSP60, E. coli GroEL, plastid Rubisco subunit binding protein and archaeal protein TF55. The TCP1 sequence has nearly 40% identity with TF55, but the similarity with HSP60 and GroEL is extremely low. |
| Application | IF, IP, FACS, WB |
| Application Notes | WB: 1/1000 IF: 1/100 Assay-dependent |
| Shipping | Shipped on dry ice. |
| Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
| Buffer | PBS, pH7.4, 50% Glycerol |
For Research Use Only. Not For Clinical Use.Related Products
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