Host Species | Rabbit |
Species Reactivity | C. elegans, Human, Mouse, Bovine, Primat |
Conjugate | NONE |
Immunogen | The region between residue 1175 and the structure of human chromosome 3 maintains the C-terminus, using the number given in entry NP_005436.1. |
Epitope | The epitope is in the AA 1175-1217 of SMC3. |
Format | Liquid or Lyophilized |
Purification | Affinity purified |
Product Overview | This product is a Rabbit antibody against the AA 1175-1217 of the SMC3. It can be used for SMC3 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation. |
Availability | Made-to-order |
Target Name | SMC3 |
Gene ID | 9126 |
UniProt ID | F5GUH4 |
Introduction | This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. |
Application | IHC, IHC-P, IP, WB |
Application Notes | Western Blot 1:10000-1:25000 Immunohistochemistry Immunohistochemistry-Paraffin 1:100-1:500 Immunoprecipitation 2-10 µL/mg |
Shipping | Shipped on dry ice. |
Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
Buffer | Tris-Citrate/Phosphate (pH 7.0-8.0) |
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