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| Host Species | Mouse |
| Species Reactivity | C. elegans, Human, Chicken, Fish, Rodent |
| Conjugate | NONE |
| Clone Number | NW0448 |
| Specificity | This antibody is binds to Human MYH7 and has cross reactivity with Chicken, Fish, Rodent. |
| Immunogen | Partially purified myosin (extracted pyrophosphate) from adult (22 years old) skeletal muscle. The immunogen sequence is C-terminal excluding the first 100 AA of the N-terminal. |
| Epitope | The epitope is in the C-terminal of MYH7 |
| Format | Liquid or Lyophilized |
| Product Overview | This product is a Mouse antibody against the C-terminal of the MYH7. It can be used for MYH7 detection in ELISA, FFPE, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot. |
| Availability | Made-to-order |
| Target Name | MYH7 |
| Gene ID | 4625 |
| UniProt ID | P12883 |
| Introduction | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. |
| Application | ELISA, FFPE, IF, IHC, IP, WB |
| Shipping | Shipped on dry ice. |
| Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
For Research Use Only. Not For Clinical Use.Related Products
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