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| Host Species | Mouse |
| Species Reactivity | C. elegans, Human, Fruit fly, Rat, Yeast |
| Conjugate | None |
| Clone Number | M38F3 |
| Specificity | This clone was chosen because it is specific to ~34 kDa Fibrillarin. |
| Immunogen | Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S. cerevisiae). |
| Format | Liquid or Lyophilized |
| Purification | Concentrated cell culture supernatant. |
| Product Overview | This product is a mouse antibody against the FBRL. It can be used for FBRL detection in Immunocytochemistry, Western Blot. |
| Availability | Made-to-order |
| Target Name | FBRL |
| Gene ID | 100195173 |
| UniProt ID | P15646 |
| Introduction | Fibrillin is part of the small subunit processing complex and is involved in the processing of pre-18S ribosomal RNA. Nop1p is a yeast homolog of fibrillin. Fibrillarin/Nop1p is unusually conserved, so yeast and human proteins are 67% identical, and human proteins can functionally replace yeast proteins. This means that an appropriate cross-reactive antibody against Nop1p/fibrillarin (such as this antibody) can be used to reveal nucleoli and study fibrillarin/Nop1p in all eukaryotes and archaea tested so far. This antibody is being widely used as a convenient marker for nucleoli in many species. |
| Application | ICC, WB |
| Application Notes | WB: 1:1000-1:10000 ICC: 1:1000-1:5000 The optimal dilution should be determined by the end user. |
| Shipping | Shipped on dry ice. |
| Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
For Research Use Only. Not For Clinical Use.Related Products
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